Symptoms & Signs
- Bone pain or tenderness
- Carpal tunnel syndrome
- Dry, shiny nails and skin
- Inability to make a fist with one or both hands
- Numbness or tingling in one or both hands
- Pain in one or both hands
- Weakness in one or both hands
- Joint contractures
- Muscle weakness
- Tenderness and swelling of the arms and legs (occasionally including joints)
- Thickened skin with puckered appearance
Diagnosis & Tests
Tests that may be done include:
- Blood tests to check for gamma globulins (a type of immune system cell) and eosinophils
- Erythrocyte sedimentation rate (ESR)
- Muscle biopsy
- Skin biopsy
Review Date : 2/22/2009
Reviewed By : Ariel D. Teitel, MD, MBA, Chief, Division of Rheumatology, St. Vincent’s Hospital, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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