Warned Cholesterol Drug Statins’s Side Effects To Memory Loss

The Food and Drug Administration Officials Tuesday added new safety alerts to the prescribing information of statins, cholesterol-reducing medications that are among the most widely prescribed drugs in the world, citing rare risks of memory loss, diabetes and muscle pain. With high dose use, the statins may cause more severe muscle pain.

Seeing more on an overview of benefits, cautions and possible side effects for common classes of cholesterol medications.

Drug class and drug names Benefits Possible side effects and cautions
Statins
Altoprev (lovastatin)
Crestor (rosuvastatin)
Lescol (fluvastatin)
Lipitor (atorvastatin)
Mevacor (lovastatin)
Pravachol (pravastatin)
Zocor (simvastatin)
Decrease LDL and triglycerides; slightly increase HDL Constipation, nausea, diarrhea, stomach pain, cramps, muscle soreness, pain and weakness; possible interaction with grapefruit juice
Bile acid binding resins
Colestid (colestipol)
Questran (cholestyramine sucrose)
Welchol (colesevelam)
Decrease LDL Constipation, bloating, nausea, gas; may increase triglycerides
Cholesterol absorption inhibitors
Zetia (ezetimibe)
Decrease LDL; slightly decrease triglycerides; slightly increase HDL Stomach pain, fatigue, muscle soreness
Combination cholesterol absorption inhibitor and statin
Vytorin (ezetimibe-simvastatin)
Decreases LDL and triglycerides; increases HDL Stomach pain, fatigue, gas, constipation, abdominal pain, cramps, muscle soreness, pain and weakness; possible interaction with grapefruit juice
Fibrates
Lofibra (fenofibrate)
Lopid (gemfibrozil)
TriCor (fenofibrate)
Decrease triglycerides; increase HDL Nausea, stomach pain, gallstones
Niacin
Niaspan (prescription niacin)
Decreases LDL and triglycerides; increases HDL Facial and neck flushing, nausea, vomiting, diarrhea, gout, high blood sugar, peptic ulcers
Combination statin and niacin
Advicor (niacin-lovastatin)
Decreases LDL and triglycerides; increases HDL Facial and neck flushing, dizziness, heart palpitations, shortness of breath, sweating, chills; possible interaction with grapefruit juice
Omega-3 fatty acids
Lovaza (prescription omega-3 fatty acid supplement)
Decreases triglycerides Belching, fishy taste, increased infection risk

 

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