What is Percodan (Aspirin Oxycodone)?

spirin is in a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing substances in the body that cause pain, fever, and inflammation.
Oxycodone is in a group of drugs called narcotic pain relievers.
The combination of aspirin and oxycodone is used to relieve moderate to severe pain.
Aspirin and oxycodone may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Percodan (Aspirin Oxycodone)?

Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye’s syndrome in children.
Stop using this medication and call your doctor at once if you have any symptoms of bleeding in your stomach or intestines. Symptoms include black, bloody, or tarry stools, and coughing up blood or vomit that looks like coffee grounds.
Oxycodone may be habit-forming and should be used only by the person it was prescribed for. Never share aspirin and oxycodone with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
Avoid drinking alcohol. It may increase your risk of stomach bleeding while taking aspirin.
Tell your doctor if the medicine seems to stop working as well in relieving your pain.

What should I discuss with my healthcare provider before taking Percodan (Aspirin Oxycodone)?

Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye’s syndrome in children.
Do not use aspirin and oxycodone if you have a bleeding or blood clotting disorder such as hemophilia. Do not use this medication if you are allergic to aspirin or oxycodone or to a non-steroidal anti-inflammatory drug (NSAID) such as Advil, Aleve, Motrin, Naprosyn, Orudis, Cataflam, Feldene, Indocin, Lodine, Mobic, Relafen, Toradol, Voltaren, and others.
Oxycodone may be habit-forming and should be used only by the person it was
Aprescribed for. Never share aspirin and oxycodone with another person, especially someone with a history of drug abuse or addiction.
If you have any of these other conditions, you may need a dose adjustment or special tests:

• asthma or other breathing disorders
• liver or kidney disease
• a history of head injury or brain tumor
• epilepsy or other seizure disorder
• stomach or intestinal disorder, history of stomach ulcer or bleeding
• a pancreas disorder
• curvature of the spine; or
• mental illness or a history of drug or alcohol addiction

FDA pregnancy category D. This medication can cause harm to an unborn baby, and breathing problems or addiction/withdrawal symptoms in a newborn. Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Do not take aspirin and oxycodone during pregnancy unless your doctor has told you to. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.
Aspirin and oxycodone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Older adults may be more sensitive to the effects of this medicine.

Percodan Side Effects

What are the possible side effects of Percodan (Aspirin Oxycodone)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

• black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee ground
• shallow breathing, slow heartbeat
• fast heart rate
• feeling light-headed, fainting
• confusion, hallucinations
• easy bruising or bleeding; or
• problems with urination

Less serious side effects may include:

• headache, dizziness, drowsiness
• heartburn, nausea, vomiting, upset stomach, bloating, gas, constipation, diarrhea
• feeling dizzy or drowsy
• headache
• sweating
• ringing in your ears; or
• dry mouth

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Percodan Interactions

What other drugs affect Percodan (Aspirin Oxycodone)?

Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy or could slow your breathing (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by aspirin and oxycodone.
Tell your doctor about all other medicines you use, especially:

• acetazolamide (Diamox)
• a diuretic (water pill)
• methotrexate (Rheumatrex, Trexall)
• steroids (prednisone and others)
• a blood thinner such as warfarin (Coumadin)
• a bronchodilator (such as Atrovent, Spiriva)
• atropine (Donnatal), dimenhydrinate (Dramamine), or scopolamine (Transderm-Scop)
• insulin or diabetes medications that you take by mouth
• an ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others
• a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others
• bowel or bladder medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin), tolterodine (Detrol) and others; or
• an NSAID such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others

This list is not complete and other drugs may interact with aspirin and oxycodone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

What should I avoid while taking Percodan (Aspirin Oxycodone)?

Aspirin and oxycodone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Ask a doctor or pharmacist before using any other over-the-counter cold, allergy, or pain medicine. Aspirin is contained in many combination medicines. Taking certain products together can cause you to get too much aspirin. Check the label to see if a medicine contains aspirin.
Avoid drinking alcohol. It may increase your risk of stomach bleeding while taking aspirin.

Percodan Dosage

How should I take Percodan (Aspirin Oxycodone)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking aspirin and oxycodone. Ask your doctor about ways to increase the fiber in your diet. Do not use a stool softener (laxative) without first asking your doctor.
You may have withdrawal symptoms when you stop using this medication after using it over a long period of time. Do not stop using the medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.
If you need surgery, tell the surgeon ahead of time that you are using aspirin and oxycodone.
Store at room temperature away from moisture, heat, and light.
Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I overdose on Percodan (Aspirin Oxycodone)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of aspirin and oxycodone can be fatal.
Overdose symptoms may include extreme drowsiness, pinpoint pupils, nausea, vomiting, diarrhea, confusion, ringing in your ears, cold or clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing.

What happens if I miss a dose of Percodan (Aspirin Oxycodone)?

Since aspirin and oxycodone is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Sourced from everydayhealth.com