What is Gammar-P I.V. (Immune Globulin Intravenous)?

Immune globulin intravenous is a sterilized solution made from human plasma. It contains the antibodies to help your body protect itself against infection from various diseases.
Immune globulin is used to treat primary immune deficiency, and to reduce the risk of infection in individuals with poorly functioning immune systems such as those with chronic lymphocytic leukemia (CLL). IGIV is also used to increase platelets (blood clotting cells) in people with idiopathic thrombocytopenic purpura (ITP) and to prevent aneurysm caused by a weakening of the main artery in the heart associated with Kawasaki syndrome.
Immune globulin is also used to treat chronic inflammatory demyelinating polyneuropathy (CIDP), a debilitating nerve disorder that causes muscle weakness and can affect daily activities.
Immune globulin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Gammar-P I.V. (Immune Globulin Intravenous)?

Immune globulin can be harmful to the kidneys, and these effects are increased when immune globulin is used together with other medicines that can harm the kidneys. Before using immune globulin, tell your doctor about all other medications you use. Many other drugs (including some over-the-counter medicines) can be harmful to the kidneys.
Before you use immune globulin intravenous, tell your doctor if you have kidney disease, diabetes (especially if you use insulin), a history of stroke or blood clot, heart disease, high blood pressure, a condition called paraproteinemia, or if you are over 65 years old.
To be sure this medication is helping your condition and is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney function may also need to be checked. Do not miss any scheduled appointments.
Using immune globulin can cause you to have unusual results with certain blood glucose tests. Tell any doctor who treats you that you are using immune globulin.
Immune globulin is made from human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although immune globulin is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

What should I discuss with my healthcare provider before taking Gammar-P I.V. (Immune Globulin Intravenous)?

You should not use this medication if you have ever had an allergic reaction to an immune globulin or if you have immune globulin A (IgA) deficiency with antibody to IgA.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely use immune globulin intravenous:

kidney disease
diabetes (especially if you use insulin)
a history of stroke or blood clot
heart disease or high blood pressure
a condition called paraproteinemia; or
if you are over 65 years old

FDA pregnancy category C. It is not known whether immune globulin is harmful to an unborn baby. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known if immune globulin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Gammar-P I.V. Side Effects

What are the possible side effects of Gammar-P I.V. (Immune Globulin Intravenous)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

urinating less than usual or not at all, swelling, weight gain, feeling short of breath
drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting
trouble breathing, blue lips
fever with headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions)
pale or yellowed skin, dark colored urine, fever, confusion or weakness
slow heart rate, weak pulse, fainting, slow breathing (breathing may stop)
sudden numbness or weakness, especially on one side of the body
sudden headache, confusion, problems with vision, speech, or balance
feeling like you might pass out
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

Less serious side effects may include:

headache
dizziness
upset stomach, mild nausea, vomiting, diarrhea
back pain, joint pain, minor chest pain
mild itching or skin rash; or
runny or stuffy nose, cough, sore throat

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Gammar-P I.V. Interactions

What other drugs affect Gammar-P I.V. (Immune Globulin Intravenous)?

Immune globulin can be harmful to the kidneys, and these effects are increased when immune globulin is used together with other medicines that can harm the kidneys. Before taking immune globulin, tell your doctor if you are also using:

lithium (Lithobid)
methotrexate (Rheumatrex, Trexall)
pain or arthritis medicines such as aspirin (Anacin, Excedrin), acetaminophen (Tylenol), diclofenac (Cataflam, Voltaren), etodolac (Lodine), ibuprofen (Advil, Motrin), indomethacin (Indocin), naproxen (Aleve, Naprosyn), and others
medicines used to treat ulcerative colitis, such as mesalamine (Pentasa) or sulfasalazine (Azulfidine)
medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) or tacrolimus (Prograf)
IV antibiotics such as amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), amikacin (Amikin), bacitracin (Baci-IM), capreomycin (Capastat), gentamicin (Garamycin), kanamycin (Kantrex), streptomycin, or vancomycin (Vancocin, Vancoled)
antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or
cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid)

This list is not complete and there may be other drugs that can interact with immune globulin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

What should I avoid while taking Gammar-P I.V. (Immune Globulin Intravenous)?

Do not receive live-virus vaccines such as measles, mumps, or rubella. The live vaccine may not work as well during this time, and may not fully protect you from disease.

Gammar-P I.V. Dosage

How should I take Gammar-P I.V. (Immune Globulin Intravenous)?

Use immune globulin intravenous exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.
Immune globulin is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.
Immune globulin intravenous should not be injected into a muscle or under the skin.
Immune globulin intravenous is usually given every 3 to 4 weeks. Your dosing schedule may be different. Follow your doctor’s instructions.
To be sure this medication is helping your condition and is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney function may also need to be checked. Do not miss any scheduled appointments.
Using immune globulin can cause you to have unusual results with certain blood glucose tests. Tell any doctor who treats you that you are using immune globulin.
Do not use the medication if it has changed colors or has any particles in it. Call your doctor for a new prescription. Throw away any unused medicine that is left over after injecting your dose.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Some brands of immune globulin should be stored in a refrigerator, while others can be kept at room temperature. Follow the directions on your prescription label or ask your pharmacist if you have questions about how to store the medication. Do not allow the medicine to freeze.

What happens if I overdose on Gammar-P I.V. (Immune Globulin Intravenous)?

Seek emergency medical attention if you think you have used too much of this medicine.

What happens if I miss a dose of Gammar-P I.V. (Immune Globulin Intravenous)?

Call your doctor for instructions if you miss a dose of this medication.
Sourced from everydayhealth.com

Gammar-P I.V.Immune Globulin Intravenous

Gammar-P I.V. (Immune Globulin Intravenous)