Alternate Names : Chorioblastoma, Trophoblastic tumor, Chorioepithelioma, Gestational trophoblastic neoplasia
Choriocarcinoma is a quick-growing form of cancer that occurs in a woman’s uterus (womb). The abnormal cells start in the tissue that would normally become the placenta, the organ that develops during pregnancy to feed the fetus.
Choriocarcinoma is a type of gestational trophoblastic disease.
- Gestational trophoblastic disease
- Hydatiform mole
Overview, Causes, & Risk Factors
Choriocarcinoma is an uncommon, but very often curable cancer associated with pregnancy. A baby may or may not develop in these types of pregnancy.
The cancer may develop after a normal pregnancy; however, it is most often associated with a complete hydatidiform mole. The abnormal tissue from the mole can continue to grow even after it is removed and can turn into cancer. About half of all women with a choriocarcinoma had a hydatidiform mole, or molar pregnancy.
Choriocarcinomas may also occur after an abortion, ectopic pregnancy, or genital tumor.
Review Date : 5/26/2008
Reviewed By : Linda Vorvick, MD, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Susan Storck, MD, FACOG, Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine; Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.