What is Acamprosate?

Acamprosate affects chemicals in the brain that may become unbalanced in a person who is addicted to alcohol. Acamprosate works by restoring this chemical balance in the brain in an alcohol-dependent person who has recently quit drinking.

Acamprosate is used to help a person who has recently quit drinking alcohol continue to choose not to drink (remain abstinent from alcohol). It is used together with behavior modification and counseling support to help you stop drinking.

Acamprosate is not likely to be helpful to a person who has not already quit drinking or undergone detoxification. It may not be helpful to a person who is also addicted to other substances besides alcohol.

Acamprosate may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking Acamprosate?

You should not use this medication if you are allergic to acamprosate, or if you have severe kidney disease.

Acamprosate will not treat or prevent alcohol withdrawal symptoms.

Before you take acamprosate, tell your doctor if you have any type of kidney problem. You may need a dose adjustment or special tests to safely use this medication.

FDA pregnancy category C. It is not known whether acamprosate is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether acamprosate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

You may have thoughts about suicide while you are taking acamprosate. Tell your doctor if you feel depressed or have any suicidal thoughts or actions during treatment.

Your family or other caregivers should also be alert to changes in your mood or behavior. Make sure your caregivers know how to contact your doctor in case you have mood changes or suicidal thoughts or actions.

Acamprosate Side Effects

What are the possible side effects of Acamprosate?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effects such as:

• mood or behavior changes
• thoughts about hurting yourself
• severe anxiety or depression
• feeling like you might pass out
• fast or pounding heartbeats
• swelling, weight gain, feeling short of breath
• confusion, increased thirst; or
• urinating less than usual or not at all

Less serious side effects may include:

• nausea, vomiting, stomach pain, loss of appetite
• constipation, diarrhea
• headache, dizziness, drowsiness
• vision problems
• problems with memory or thinking
• weakness, cold or flu-like symptoms
• back pain, joint or muscle pain
• dry mouth, decreased or distorted sense of taste
• sleep problems (insomnia)
• impotence, loss of interest in sex
• sweating, mild skin rash; or
• numbness or tingly feeling

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Acamprosate Interactions

What other drugs affect Acamprosate?

There may be other drugs that can interact with acamprosate. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

What should I avoid while taking Acamprosate?

Acamprosate can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Acamprosate Dosage

How should I take Acamprosate?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Acamprosate treatment should be started as soon as possible after you have quit drinking.

Take this medicine with water.

Acamprosate is usually taken 3 times daily, and may be taken with or without food. If you regularly eat 3 meals per day, it may help you remember to take your acamprosate if you take a dose with each meal. Follow your doctor’s instructions.

Acamprosate is only part of a complete program of treatment that also includes counseling support and continued abstinence from alcohol.

Take this medication for the full prescribed length of time, even if you relapse and drink alcohol. While you are taking acamprosate, tell your doctor about any alcoholic drinks you consume, no matter how many.

It is important to use acamprosate regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store acamprosate at room temperature away from moisture and heat.

Back to Top

What happens if I overdose on Acamprosate?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose can cause diarrhea but is not expected to produce serious side effects.

What happens if I miss a dose of Acamprosate?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

Sourced from everydayhealth.com