What is Phenoxybenzamine?

Phenoxybenzamine lowers blood pressure.
Phenoxybenzamine is used control blood pressure and reduce sweating in people with pheochromocytoma.
Phenoxybenzamine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Phenoxybenzamine?

You should not use this medication if you are allergic to phenoxybenzamine.
Before taking phenoxybenzamine, tell your doctor if you have coronary artery disease, a lung infection, or kidney disease.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid drinking alcohol. It can increase drowsiness caused by phenoxybenzamine.
This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What should I discuss with my healthcare provider before taking Phenoxybenzamine?

You should not use this medication if you are allergic to phenoxybenzamine.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

• coronary artery disease (hardened arteries)
• a lung infection; or
• kidney disease

FDA pregnancy category C. It is not known whether phenoxybenzamine is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether phenoxybenzamine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Phenoxybenzamine Side Effects

What are the possible side effects of Phenoxybenzamine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using phenoxybenzamine and call your doctor at once if you severe dizziness or if you feel like you might pass out.
Less serious side effects may include:

• stuffy nose
• mild dizziness or drowsiness
• blurred vision
• trouble having an orgasm
• upset stomach; or
• tired feeling

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Phenoxybenzamine Interactions

What other drugs affect Phenoxybenzamine?

Tell your doctor about all other medications you use, especially:

• reserpine
• tizanidine (Zanaflex)
• epinephrine (Epi-Pen), norepinephrine; or
• blood pressure medications

This list is not complete and there may be other drugs that can interact with phenoxybenzamine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

What should I avoid while taking Phenoxybenzamine?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid drinking alcohol. It can increase drowsiness caused by phenoxybenzamine.

Phenoxybenzamine Dosage

How should I take Phenoxybenzamine?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take this medicine with a full glass of water.
Store phenoxybenzamine at room temperature away from moisture and heat.

What happens if I overdose on Phenoxybenzamine?

Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include fast heart rate, vomiting, dizziness, or fainting.

What happens if I miss a dose of Phenoxybenzamine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
Sourced from everydayhealth.com