What is Magnevist (Gadopentetate Dimeglumine)?

Gadopentetate dimeglumine is a contrast agent. Gadopentetate dimeglumine produces magnetic effects. It is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.
Gadopentetate dimeglumine is used to help diagnose certain disorders of the heart, brain, blood vessels, and spinal tissues.
Gadopentetate dimeglumine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Magnevist (Gadopentetate Dimeglumine)?

Gadopentetate dimeglumine can cause a life-threatening condition in people with advanced kidney disease who are undergoing an MRI. The symptoms of this condition include:

burning, itching, swelling, and tightening or hardening of your skin
muscle weakness
pain or stiffness in your arms, hands, legs, or feet
deep bone pain in your ribs or your hips
yellow patches on the whites of your eyes; or
skin redness or discoloration

Before receiving this medication, tell your doctor if you have kidney disease. You may not be able to receive an MRI with gadopentetate dimeglumine.
Tell your doctor if you have liver disease, a seizure disorder, sickle cell or hemolytic anemia, a history of stroke or blood clots, a recent head or brain injury, asthma or allergies, or if you are on dialysis.
Your doctor or other healthcare provider may want to watch you for a short time after your test is over. This is to make sure you do not have any unwanted side effects or delayed reactions.
Some of the side effects of gadopentetate dimeglumine can occur up to 24 hours after you have received the medication.

What should I discuss with my healthcare provider before taking Magnevist (Gadopentetate Dimeglumine)?

Gadopentetate dimeglumine can cause a life-threatening condition in people with advanced kidney disease who are undergoing an MRI. The symptoms of this condition include:

burning, itching, swelling, and tightening or hardening of your skin
muscle weakness
pain or stiffness in your arms, hands, legs, or feet
deep bone pain in your ribs or your hips
yellow patches on the whites of your eyes; or
skin redness or discoloration

Before receiving this medication, tell your doctor if you have kidney disease. You may not be able to receive an MRI with gadopentetate dimeglumine.
Before receiving gadopentetate dimeglumine, tell your doctor if you have ever had any type of reaction to another contrast agent, or if you have:

a recent head or brain injury
epilepsy or other seizure disorder
liver disease
sickle cell disease or hemolytic anemia
a history of stroke, blood clots, or circulation problems
asthma, hay fever, or a history of food or drug allergies; or
if you are on dialysis

If you have any of these conditions, you may not be able to receive gadopentetate dimeglumine, or you may need a dose adjustment or special tests during treatment.
FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before you receive gadopentetate dimeglumine, tell your doctor if you are pregnant or plan to become pregnant during treatment.
Gadopentetate dimeglumine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Magnevist Side Effects

What are the possible side effects of Magnevist (Gadopentetate Dimeglumine)?

Some of the side effects of gadopentetate dimeglumine can occur up to 24 hours after you have received the medication.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

seizure (convulsions)
urinating more or less than usual, or not at all
feeling light-headed, fainting
skin changes where the injection was given; or
fast, uneven heart rate

ess serious side effects may include:

headache, dizziness, anxiety
nausea, vomiting, loss of appetite
increased thirst
chills
numbness or tingly feeling
cold feeling, warmth, pain, or burning where the injection was given; or
stuffy nose, sore throat

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Magnevist Interactions

What other drugs affect Magnevist (Gadopentetate Dimeglumine)?

There may be other drugs that can affect gadopentetate dimeglumine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs presc
ribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Magnevist (Gadopentetate Dimeglumine)?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity after you receive gadopentetate dimeglumine.

Magnevist Dosage

How should I take Magnevist (Gadopentetate Dimeglumine)?

Gadopentetate dimeglumine is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting during your MRI.
Your doctor or other healthcare provider may want to watch you for a short time after your test is over. This is to make sure you do not have any unwanted side effects or delayed reactions.

What happens if I overdose on Magnevist (Gadopentetate Dimeglumine)?

Seek emergency medical attention if you think you have received too much of this medicine. Symptoms of a gadopentetate dimeglumine overdose are not known.

What happens if I miss a dose of Magnevist (Gadopentetate Dimeglumine)?

Since gadopentetate dimeglumine is used only during your MRI, you will not be on a dosing schedule.
Edited from everydayhealth.com

Gadopentetate Dimeglumine Magnevist

Magnevist (Gadopentetate Dimeglumine)