What is Amphadase (Hyaluronidase)?
Hyaluronidase is a genetically designed protein.
Hyaluronidase is used as an aid in helping your body absorb other injected medications.
Hyaluronidase is also used to help contrast dyes in your body show more clearly on certain types of x-rays or scans.
Hyaluronidase may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Amphadase (Hyaluronidase)?
Your doctor may perform a skin test to see if you are allergic to hyaluronidase before you receive the medication.
Before receiving hyaluronidase, tell your doctor if you are using any of the following drugs: furosemide (Lasix); phenytoin (Dilantin); a sedative or anxiety medication (such as Valium, Xanax, Tranxene); aspirin or salicylates; cortisone or ACTH (Corticotropin); estrogens; or an antihistamine (such as a cold or allergy medicine).
What should I discuss with my healthcare provider before taking Amphadase (Hyaluronidase)?
Your doctor may perform a skin test to see if you are allergic to hyaluronidase before you receive the medication.
FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before you receive hyaluronidase, tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known if hyaluronidase passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.
Amphadase Side Effects
What are the possible side effects of Amphadase (Hyaluronidase)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
- pain or tenderness where the medication was injected; or
- swelling in any part of your body
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Amphadase Interactions
What other drugs affect Amphadase (Hyaluronidase)?
Before receiving hyaluronidase, tell your doctor if you are using any of the following drugs:
- furosemide (Lasix)
- phenytoin (Dilantin)
- a sedative or anxiety medication (such as Valium, Xanax, Tranxene)
- aspirin or salicylates
- cortisone or ACTH (Corticotropin)
- estrogens; or
- an antihistamine (such as a cold or allergy medicine)
This list is not complete and there may be other drugs that can interact with hyaluronidase. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
What should I avoid while taking Amphadase (Hyaluronidase)?
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using hyaluronidase.
Amphadase Dosage
How should I take Amphadase (Hyaluronidase)?
This medication is given as an injection under the skin. You will receive the injection from a doctor or other healthcare professional.
What happens if I overdose on Amphadase (Hyaluronidase)?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a hyaluronidase overdose may include itching or swelling where the injection was given. Other possible symptoms include chills, dizziness, nausea, vomiting, fast heartbeat, or fainting.
What happens if I miss a dose of Amphadase (Hyaluronidase)?
Call your doctor for instructions if you miss an appointment for your hyaluronidase injection.
Edited from everydayhealth.com